The Center is equipped for traditional organic synthesis and for more demanding batch applications (such as experiments under strictly controlled atmosphere, high pressure and microwave applications). Notable routine equipment include:

• CEM Discovery SP with Active Vent for microwave activation at the research scale
• Metrohm Karl-Fischer coulometer for titration of water content (dry solvents and reagents)
• Parr reactor for high-pressure reactions
• Various cryostats for low temperature reactions
• High-power LEDs for photochemical reactions

Magritek Spinsolve NMR Spectrometer

Benchtop 43 MHz NMR spectrometer available for 1H, 19F and 31P, both for traditional analysis and in-line monitoring.

Shimadzu IRSpirit Spectrometer

FTIR spectrometer equipped with a diamond crystal and QATR-S accessory for the qualitative and  quantitative analysis of solids and oils.

Shimadzu LC-2030 and LC-2050

Two High-Pressure Liquid Chromatographs for high-throughput analysis of mixtures and pure compounds.

Shimadzu LCMS-2020

Mass Spectrometer for positive and negative ions detection and analysis.

Shimadzu GC-2014

Gas chromatrograph with FID (Flame Ionization Detector) and autosampler for routine analysis of reaction mixtures (qualitative and quantitative).

Teledyne CombiFlash Nextgen300+

Two automated flash chromatography apparatus equipped with UV-vis and ELSD detectors for rapid purification of samples. They operate from 1 to 300 mL/min and up to 20 bars.

The Center owns a remarkable set of continuous flow reactors for demanding applications including liquid-liquid, gas-liquid, photochemistry, high temperature/pressure applications and complex multistep sequences.

Standard fluidic equipment for daily research activities includes a range of injection systems (Nexus Fusion 6000 syringe pumps, Asia Syrris continuous syringe pumps, Knauer and Thales Nano HPLC pumps), gas flow controlers, pressure regulators (including variable BPRs) and in-line purification modules (e.g. Zaiput membrane-based liquid-liquid separators).

Corning Advanced-flow Lab Photo Reactor

Continuous flow reactor equipped for photochemical lab scale applications
Typical applications: lab scale process, R&D, optimization, lab-scale production for liq-liq, liq-gas, thermal or photochemical applications
Light source: high power LEDs (multiple wavelengths available)
Wetted-parts: metal free, glass, perfluorinated polymers, PEEK
Internal volume: 2.7 mL
Scale: 100+g/day
Operating conditions: -25 °C to 200 °C, up to 18 bar

Corning Advanced-flow Low Flow Reactor

Continuous flow reactor for lab scale applications
Typical applications: lab scale process, R&D, optimization, lab-scale production for liq-liq, liq-gas, thermal applications
Wetted-parts: metal free, glass, perfluorinated polymers, PEEK
Internal volume: 0.5 mL (per fluidic module)
Scale: 100+g/day
Operating conditions: -25 °C to 200 °C, up to 18 bar

Phoenix Flow Reactor (ThalesNano)

Continuous flow high temperature reactor compatible for homogeneous and heterogeneous liquid-liquid or gas liquid reactions.
Typical applications: lab scale process, R&D, optimization, lab-scale production for liq-liq, liq-gas, high temperature applications
Wetted-parts: SS
Internal volume: 0.9 to 18 mL
Scale: up to 100+g/day
Operating conditions: up to 450 °C, up to 100 bar

CEM Discovery SP

Microwave reactor equipped with flow cells for continuous flow applications
Typical applications: lab scale continuous flow MW optimization and production
Wetted-parts: glass, perfluorinated polymers, PEEK
Flow rate: 0.1 – 10 mL/min
Internal volume: up to 30 mL
Scale: 100+g/day
Operating conditions: up to 300 °C

Flow IR (Mettler Toledo)

Device for in-line IR analysis equipped with a DTGS detector using HappGenzel apodization and a Silicon probe. High pressure flow heated cels of 10 or 50 µL are available.

3D printing

The lab is equipped with various tools to manufacture custom parts, including a Prusa MK3 and two Prusa MINI 3D-printers. They are used for the production of tools and the prototyping of in-house devices in PLA, PETG and PP.

Analytical support

Major analytical instrumentation (NMR, MS spectrometers, etc.) is provided by the Department of Chemistry and fellow laboratories:

• Center for Nuclear Magnetic Resonance (CREMAN): 400 MHz and 700 MHz spectrometers
• Laboratory of Mass Spectrometry
• Center for Education and Research on Macromolecules (CERM)

Computational support

Computational support for high-demanding calculations is provided by the University of Liège and the CéCI consortium of high-performance computing centers.

• SEGI – computational resources at the University of Liège
• CéCI – consortium of high-performance computing centers